Colangitis esclerosante asociada a infección severa por SARS-CoV-2

Autores/as

DOI:

https://doi.org/10.52784/27112330.161

Palabras clave:

SARS-CoV-2, colangitis esclerosante secundaria, enfermedad crítica, COVID-19, ácido ursodesoxicólico, trasplante.

Resumen

La colangitis esclerosante secundaria es una enfermedad poco prevalente, de etiología multifactorial y con una fisiopatología progresiva, caracterizada por obstrucción biliar y fibrosis. Entre las múltiples causas se destacan las siguientes: inmunomediada por IgG4, isquémica, infecciosa y relacionada a medicamentos. En el contexto de la pandemia por SARS-CoV-2, se han reportado algunas series de casos que determinan una asociación entre estas dos entidades. Se presenta el caso de una mujer en la octava década de la vida con infección por SARS-CoV-2 grave, que cursó con ictericia progresiva, perfil hepático con patrón colestásico, y hallazgos imagenológicos de colangitis esclerosante con vía biliar desestructurada de manera difusa, microcálculos y barro biliar. Se diagnosticó colangitis esclerosante secundaria a SARS-CoV-2 y se dio manejo con ácido ursodesoxicólico.

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Biografía del autor/a

Natalia Torres-Vellojín, Universidad de Antioquia

Estudiante de Medicina, Universidad de Antioquia. Medellín, Colombia.

Juan Camilo Díaz-Duque, Universidad de Antioquia

Estudiante de Medicina, Universidad de Antioquia. Medellín, Colombia.

Luz Adriana Gómez-Ramírez, Hospital Pablo Tobón Uribe

Médica General, Hospitalización, Hospital Pablo Tobón Uribe. Medellín, Colombia.

Octavio G. Muñoz-Maya, Hospital Pablo Tobón Uribe, Universidad de Antioquia

Médico, Especialista en Medicina Interna, Especialista en Hepatología Clínica y Trasplante Hepático, Hospital Pablo Tobón Uribe, Universidad de Antioquia. Medellín, Colombia.

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Publicado

2022-07-05

Cómo citar

Torres-Vellojín, N., Díaz-Duque, J. C., Gómez-Ramírez, L. A., & Muñoz-Maya, O. G. (2022). Colangitis esclerosante asociada a infección severa por SARS-CoV-2. Hepatología, 3(2), 225–232. https://doi.org/10.52784/27112330.161

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